How Does Viagra Work? Breaking Down Its Mechanism of Action

6/9/20211 min read

Introduction
Viagra is one of the most well-known treatments for erectile dysfunction (ED), but how exactly does it work? This post explains the science behind Viagra in simple terms and what happens in the body when you take the pill.

What is Viagra?
Viagra, with the active ingredient sildenafil, is a medication used to treat erectile dysfunction. ED is often caused by reduced blood flow to the penis, making it difficult for men to achieve or maintain an erection.

The Role of PDE5 Inhibitors
Viagra belongs to a class of drugs called PDE5 inhibitors. PDE5 is an enzyme that breaks down cGMP, a substance that helps control blood flow. By inhibiting PDE5, Viagra allows cGMP to accumulate, leading to increased blood flow to the penis, which is necessary for an erection.

How Viagra Improves Blood Flow
When a man is sexually aroused, nitric oxide is released in the penis, stimulating the production of cGMP. This causes the blood vessels in the penis to relax and widen, allowing more blood to flow in. Viagra amplifies this process, ensuring that the blood vessels remain relaxed long enough to produce and sustain an erection.

Timing and Duration
Viagra usually takes effect 30-60 minutes after ingestion and lasts for about 4-5 hours. It doesn’t cause an erection on its own but requires sexual stimulation to be effective.

Conclusion
Understanding how Viagra works helps demystify the medication and can empower men to seek the right treatment for ED. Always consult with a doctor to determine whether Viagra is right for you.